Nights Gets Real Weather
Sega Japan announced today that the upcoming Wii revival of the Nights franchise will be the first game to directly interact with the Wii Weather Channel.
Nights: Journey of Dreams will use the free Wii module for its "My Dream" area, where players get to freely interact with the game's "A-Life" artificially-driven creatures. The weather in this area of the game will reflect the weather of the location that you've registered with the Wii Weather Channel. Depending on the weather outside, you might see clear skies, or thick cloud cover. The game will also replicate snow and thunder storms.
The A-life creatures change their behavior based on the season, time of day, and weather, so this little bit of added reality should contribute greatly to the game.

Source: http://au.wii.ign.com/articles/832/832597p1.html